JAMSS Japan Manned Space Systems Corporation


Innovation of utilizing microgravity environment in space

Kirara Space-made Protein Crystal

Support your drug discovery and research in space.
Also used for purposes other than protein crystallization.

Kirara service is to support drug discovery through high-quality protein crystallization in space with our original small incubator unit in ICE Cubes Facility in the International Space Station.

Under the microgravity environment of the ISS, large and/or high-quality crystals are expected to be produced compared with ground environment since gravity-driven convection and sedimentation are suppressed.

New utilization in space environment

  • New utilization in space environment
  • New utilization in space environment
  • High-quality protein crystal
    Large crystals for neutron analysis
  • Enzymatic synthesis of cellulose,
    which was achieved
    by Kirara first time in the world
  • COVID-19 Drug Discovery Research

Service Flow

One-Stop Service of crystallization in space.
Launched within 4 month after application.

Schedule Task By Action
4 months before launch Application Customer Submission of application data sheet
Safety check JAMSS Evaluate the safety of protein samples, reagents etc.
Contract Customer Agreement of the contract
3 months before launch Sample delivery Customer Delivery of protein samples and reagents with Datasheet for optimization
2 months before launch Mission prep JAMSS Optimization of on-orbit crystallization conditions etc.

Launch to the ISS, Crystallization onboard

1 month after launch Return JAMSS Return of samples from the ISS
1 month after return Delivery Customer Return samples to users.
Submission of Datasheet for freezing crystals or X-ray diffraction when necessary

Application form including date sheets of sample(s)
Note that one Excel file contains several data sheets to be submitted per the service flow above.


Data Sheets

Application sheet/Datasheet for optimization/Datasheet for freezing crystals or X-ray diffraction


Kirara Application Guidelines

High-quality protein crystal production service Usage guidance
  • Guideline for
    sample transportation

  • Sample handling
    after return from space


Kirara #4 Mission will be launched in NET Jan 2023.


High-quality protein crystals obtained in space.

Improvement in the resolution of the crystal grown in space was observed in Kirara #1 mission conducted in December 2019.
Please see "Technical Document" for details.





Growing large crystals for neutron diffraction

The research team lead by Ms. Sora Yamaguchi, Dr. Naoki Sunagawa and Professor Kiyohiko Igarashi from the Graduate School of Agricultural and Life Sciences, the University of Tokyo, obtained large-scale crystals of PcCel6A mutant under microgravity in space using a large bore quartz capillary developed by our partner Confocal Science Inc.
Please see "Technical Document" for details.

Crystal of the PcCel6A mutant obtained in Kirara Crystal of the PcCel6A mutant obtained in Kirara

Crystal of the PcCel6A mutant obtained in Kirara

Reference: "Preparation of Large-Volume Crystal of Cellulase Under Microgravity to Investigate the Mechanism of Thermal Stabilization" Sora YAMAGUCHI, Naoki SUNAGAWA, Kaori MATSUYAMA, Mikako TACHIOKA, Erika HIROTA, Sachiko TAKAHASHI, Kiyohiko IGARASHI., Int. J. Microgravity Sci.Appl. 38(1) 380103 (2021)

First cellulose synthesis by enzyme in space
for the first time in the world

The research team lead by Mr. Yudai Kuga, Dr. Naoki Sunagawa and Professor Kiyohiko Igarashi from the Graduate School of Agricultural and Life Sciences, the University of Tokyo, synthesized cellulose enzymatically under the microgravity environment of space for the first time in the world.

Cellulose enzymatically synthesized on the ground is heterogeneously synthesized Cellulose enzymatically synthesized in microgravity is uniformly synthesized

Reference: "Enzymatic synthesis of cellulose in space: gravity is a crucial factor for building cellulose II gel structure" Tomohiro Kuga, Naoki Sunagawa, Kiyohiko Igarashi., Cellulose, 29 January 2022

COVID-19 Drug Discovery Research

InnoStudio launched their samples of remdesivir-SBECD to the ISS in Kirara#2. It was the first space experiment for COVID-19 drug discovery research in the world by the investigation of JAMSS and InnoStudio.
This mission was also featured on the ESA website

For Education/Promotion

Kirara is also available for educational and promotional projects.
Kirara can be used in STEAM program using the ISS, “Kirara Science Program.” Kirara offers an extremely rare experience for students to be familiar with the space and science. They can do "real" space experiment to grow protein crystals in space.
If Kirara open slot is available and it fits in the slot, Kirara brings your item to space. They cannot be for pure commercial purposes but can be used for SDGs and STEAM activities. Kirara also offers label space on surface and accommodates SD cards inside the Cube. They were used for SDGs activity by school children.

*STEAM education is the educational method that combines science, technology, engineering, arts, and mathematics.

For Education/Promotion For Education/Promotion

Cooperation partners


You can apply Kirara service by sending the application form to jamss-kirara@jamss.co.jp.
If you have any questions, please use inquiry forms below: